ETHYL(3-HYDROXYISOAMYL)BARBITURIC ACID AS THE PRINCIPAL METABOLITE OF AMYTAL
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چکیده
منابع مشابه
Ethyl (3-hydroxyisoamyl) barbituric acid as the principal metabolite of amytal.
An earlier study (1) from this laboratory proved conclusively that Amytal, 5-ethyl-5-isoamylbarbituric acid (I), is not detoxified by simple hydrolysis of the barbituric acid ring and indicated that the alkyl side chain (or chains) must suffer alteration in viva. Recently (2), it was discovered that the isomeric drug, pentobarbital, is excreted as the diastereoisomers of 5-ethyl-5-(3-hydroxy-1-...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1952
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(19)50912-7